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EYE VISION ANTIAGING & WELLNESS NEWS

10/25/09 - Gene therapy transforms eyesight of 12 born with rare defect A single injection in a patient's eye brings 'astounding' results. The findings may offer hope for those with macular degeneration and retinitis pigmentosa. Corey Haas Corey Haas, foreground, has significant improvement in his vision after receiving gene therapy. With him are his parents, Ethan and Nancy, and two research leaders: Dr. Katherine A. High, left, and Dr. Jean Bennett, right. (Daniel Burke Photography) * Related * Video: Patient after gene-therapy eye injection * Video: Patient before gene-therapy eye injection * As genetic testing races ahead, doctors are left behind By Thomas H. Maugh II October 25, 2009 * EmailE-mail * printPrint * Share * increase text size decrease text size Text Size Pennsylvania researchers using gene therapy have made significant improvements in vision in 12 patients with a rare inherited visual defect, a finding that suggests it may be possible to produce similar improvements in a much larger number of patients with retinitis pigmentosa and macular degeneration. The team last year reported success with three adult patients, an achievement that was hailed as a major accomplishment for gene therapy. They have now treated an additional nine patients, including five children, and find that the best results are achieved in the youngest patients, whose defective retinal cells have not had time to die off.

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