VitaMineralMIX NEW!!

Discussion:

The essential amino acid (EAA) composition that comprises VitaMineralMIX was developed by internationally recognized researchers in the fields of muscle metabolism as well as aging and longevity. This blend has been meticulously refined over the last several decades and is the subject of multiple patents, including for improved muscle recovery1 and improved muscle protein synthesis.

 * Quality Not Quantity Of the 20 amino acids (AA) that make up proteins found in the human body, 9 are deemed essential, meaning that they cannot be produced endogenously and must be consumed through dietary means.

The EAAs are primarily responsible for the biological process of muscle protein synthesis in both the young and older populations.

 Moreover, studies demonstrate that there is no additional benefit to muscle protein synthesis from adding nonessential AAs to an EAA supplement. For instance, compared with the provision of 3.6 g of EAAs alone, the addition of 3.6 g of nonessential AAs produced no additional benefit to net muscle balance.

Likewise, an EAA supplement bolus—15 g with the 9 EAAs in similar ratios to the patented blend—had twice the impact on muscle protein synthesis as that of an equal amount of high-quality protein.

Why Include Arginine? Arginine is considered a conditionally essential amino acid, meaning that under certain pathophysiological conditions, its synthesis is limited and fails to meet physiological needs.

 In healthy young adults, sufficient arginine can be synthesized to meet normal demands. However, during rapid growth or in response to stress, there are heightened needs for arginine that may not be fully met. Furthermore, there is evidence that arginine has a unique stimulatory effect on muscle protein synthesis. While all mechanisms have not been fully elucidated and are likely multifactorial, it is known that arginine converts to nitric oxide, which relaxes blood vessels and improves blood flow to muscles. Additionally, arginine availability influences its own catabolism and that of other amino acids by controlling ureagenesis, the elimination of nitrogenous waste of protein metabolism. This critical finding solidified the need to add arginine to the EAA formulation because without it, plasma arginine decreases, therefore potentially reducing the rate of endogenous protein synthesis.

* Essential Amino Acids and Exercise Gains in muscle mass and quality attributed to the stimulation of muscle protein synthesis by EAAs can translate to improved physical performance and functional outcomes.3,5 Ingestion of EAA immediately before or after resistance exercise can impact an anabolic response in skeletal muscle, but AA uptake may be greater when consumed before exercise, which could be attributed to the stimulatory effect of exercise on blood flow.

Additionally, free-form EAAs are often considered for use over intact proteins before rigorous exercise because they are rapidly absorbed, require little to no digestion, and confer minimal gastric load.